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Registro Completo |
Biblioteca(s): |
Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
Data corrente: |
31/08/2022 |
Data da última atualização: |
31/08/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CAMPOS, G. S.; CARDOSO, F. F.; GULIAS GOMES, C. C.; DOMINGUES, R.; REGITANO, L. C. de A.; OLIVEIRA, M. C. de S.; OLIVEIRA, H. N. DE; CARVALHEIRO, R.; ALBUQUERQUE, L. G.; MILLER, S.; MISTZAL, I.; LOURENCO, D. |
Afiliação: |
GABRIEL SOARES CAMPOS, University of Georgia; FERNANDO FLORES CARDOSO, CPPSUL; CLAUDIA CRISTINA GULIAS GOMES, CPPSUL; ROBERT DOMINGUES, CPPSUL; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; MARCIA CRISTINA DE SENA OLIVEIRA, CPPSE; HENRIQUE NUNES DE OLIVEIRA, UNESP; ROBERTO CARVALHEIRO, UNESP; LUCIA GALVÃO ALBUQUERQUE, UNESP; STEPHEN MILLER, Angus Genetics Inc.; IGNACY MISZTAL, University of Georgia; DANIELA LOURENCO, University of Georgia. |
Título: |
Development of genomic predictions for Angus cattle in Brazil incorporating genotypes from related american sires. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Journal of Animal Science, v. 100, n. 2, p. 1-13, Feb. 2022. |
DOI: |
https://doi.org/10.1093/jas/skac009 |
Idioma: |
Inglês |
Notas: |
skac009. |
Conteúdo: |
Genomic prediction has become the new standard for genetic improvement programs, and currently, there is a desire to implement this technology for the evaluation of Angus cattle in Brazil. Thus, the main objective of this study was to assess the feasibility of evaluating young Brazilian Angus (BA) bulls and heifers for 12 routinely recorded traits using single-step genomic BLUP (ssGBLUP) with and without genotypes from American Angus (AA) sires. The second objective was to obtain estimates of effective population size (Ne) and linkage disequilibrium (LD) in the Brazilian Angus population. The dataset contained phenotypic information for up to 277,661 animals belonging to the Promebo breeding program, pedigree for 362,900, of which 1,386 were genotyped for 50k, 77k, and 150k single nucleotide polymorphism (SNP) panels. After imputation and quality control, 61,666 SNPs were available for the analyses. In addition, genotypes from 332 American Angus (AA) sires widely used in Brazil were retrieved from the AA Association database to be used for genomic predictions. Bivariate animal models were used to estimate variance components, traditional EBV, and genomic EBV (GEBV). Validation was carried out with the linear regression method (LR) using young-genotyped animals born between 2013 and 2015 without phenotypes in the reduced dataset and with records in the complete dataset. Validation animals were further split into progeny of BA and AA sires to evaluate if their progenies would benefit by including genotypes from AA sires. The Ne was 254 based on pedigree and 197 based on LD, and the average LD (±SD) and distance between adjacent single nucleotide polymorphisms (SNPs) across all chromosomes were 0.27 (±0.27) and 40743.68 bp, respectively. Prediction accuracies with ssGBLUP outperformed BLUP for all traits, improving accuracies by, on average, 16% for BA young bulls and heifers. The GEBV prediction accuracies ranged from 0.37 (total maternal for weaning weight and tick count) to 0.54 (yearling precocity) across all traits, and dispersion (LR coefficients) fluctuated between 0.92 and 1.06. Inclusion of genotyped sires from the AA improved GEBV accuracies by 2%, on average, compared to using only the BA reference population. Our study indicated that genomic information could help us to improve GEBV accuracies and hence genetic progress in the Brazilian Angus population. The inclusion of genotypes from American Angus sires heavily used in Brazil just marginally increased the GEBV accuracies for selection candidates. MenosGenomic prediction has become the new standard for genetic improvement programs, and currently, there is a desire to implement this technology for the evaluation of Angus cattle in Brazil. Thus, the main objective of this study was to assess the feasibility of evaluating young Brazilian Angus (BA) bulls and heifers for 12 routinely recorded traits using single-step genomic BLUP (ssGBLUP) with and without genotypes from American Angus (AA) sires. The second objective was to obtain estimates of effective population size (Ne) and linkage disequilibrium (LD) in the Brazilian Angus population. The dataset contained phenotypic information for up to 277,661 animals belonging to the Promebo breeding program, pedigree for 362,900, of which 1,386 were genotyped for 50k, 77k, and 150k single nucleotide polymorphism (SNP) panels. After imputation and quality control, 61,666 SNPs were available for the analyses. In addition, genotypes from 332 American Angus (AA) sires widely used in Brazil were retrieved from the AA Association database to be used for genomic predictions. Bivariate animal models were used to estimate variance components, traditional EBV, and genomic EBV (GEBV). Validation was carried out with the linear regression method (LR) using young-genotyped animals born between 2013 and 2015 without phenotypes in the reduced dataset and with records in the complete dataset. Validation animals were further split into progeny of BA and AA sires to evaluate if their progenies would ... Mostrar Tudo |
Palavras-Chave: |
Angus cattle; GEBV accuracies; Genetic improvement programs; Genomic prediction; Genotypes from American Angus. |
Thesagro: |
Gado de Corte; Genoma; Genótipo; Seleção Genética; Seleção Genótipa. |
Categoria do assunto: |
G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1145926/1/skac009.pdf
|
Marc: |
LEADER 03755naa a2200397 a 4500 001 2145926 005 2022-08-31 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1093/jas/skac009$2DOI 100 1 $aCAMPOS, G. S. 245 $aDevelopment of genomic predictions for Angus cattle in Brazil incorporating genotypes from related american sires.$h[electronic resource] 260 $c2022 500 $askac009. 520 $aGenomic prediction has become the new standard for genetic improvement programs, and currently, there is a desire to implement this technology for the evaluation of Angus cattle in Brazil. Thus, the main objective of this study was to assess the feasibility of evaluating young Brazilian Angus (BA) bulls and heifers for 12 routinely recorded traits using single-step genomic BLUP (ssGBLUP) with and without genotypes from American Angus (AA) sires. The second objective was to obtain estimates of effective population size (Ne) and linkage disequilibrium (LD) in the Brazilian Angus population. The dataset contained phenotypic information for up to 277,661 animals belonging to the Promebo breeding program, pedigree for 362,900, of which 1,386 were genotyped for 50k, 77k, and 150k single nucleotide polymorphism (SNP) panels. After imputation and quality control, 61,666 SNPs were available for the analyses. In addition, genotypes from 332 American Angus (AA) sires widely used in Brazil were retrieved from the AA Association database to be used for genomic predictions. Bivariate animal models were used to estimate variance components, traditional EBV, and genomic EBV (GEBV). Validation was carried out with the linear regression method (LR) using young-genotyped animals born between 2013 and 2015 without phenotypes in the reduced dataset and with records in the complete dataset. Validation animals were further split into progeny of BA and AA sires to evaluate if their progenies would benefit by including genotypes from AA sires. The Ne was 254 based on pedigree and 197 based on LD, and the average LD (±SD) and distance between adjacent single nucleotide polymorphisms (SNPs) across all chromosomes were 0.27 (±0.27) and 40743.68 bp, respectively. Prediction accuracies with ssGBLUP outperformed BLUP for all traits, improving accuracies by, on average, 16% for BA young bulls and heifers. The GEBV prediction accuracies ranged from 0.37 (total maternal for weaning weight and tick count) to 0.54 (yearling precocity) across all traits, and dispersion (LR coefficients) fluctuated between 0.92 and 1.06. Inclusion of genotyped sires from the AA improved GEBV accuracies by 2%, on average, compared to using only the BA reference population. Our study indicated that genomic information could help us to improve GEBV accuracies and hence genetic progress in the Brazilian Angus population. The inclusion of genotypes from American Angus sires heavily used in Brazil just marginally increased the GEBV accuracies for selection candidates. 650 $aGado de Corte 650 $aGenoma 650 $aGenótipo 650 $aSeleção Genética 650 $aSeleção Genótipa 653 $aAngus cattle 653 $aGEBV accuracies 653 $aGenetic improvement programs 653 $aGenomic prediction 653 $aGenotypes from American Angus 700 1 $aCARDOSO, F. F. 700 1 $aGULIAS GOMES, C. C. 700 1 $aDOMINGUES, R. 700 1 $aREGITANO, L. C. de A. 700 1 $aOLIVEIRA, M. C. de S. 700 1 $aOLIVEIRA, H. N. DE 700 1 $aCARVALHEIRO, R. 700 1 $aALBUQUERQUE, L. G. 700 1 $aMILLER, S. 700 1 $aMISTZAL, I. 700 1 $aLOURENCO, D. 773 $tJournal of Animal Science$gv. 100, n. 2, p. 1-13, Feb. 2022.
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Registro original: |
Embrapa Pecuária Sul (CPPSUL) |
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Registros recuperados : 20 | |
1. | | ATAIDES, K. da S.; SHIOTSUKI, L.; GARCIA, B. F.; SILVA, D. A.; VARGAS, G.; CARVALHEIRO, R. Impacto do efeito de ambiente comum em características morfométricas de tambaqui (Colossoma macropomum) avaliadas aos 6 e 12 meses de idade. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 14., 2021, Santa Catarina. Passado, presente e futuro: anais. Santa Catarina: Sociedade Brasileira de Melhoramento Animal, 2021.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Pesca e Aquicultura. |
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2. | | CHUD, T. C. S.; VENTURA, R. V.; SCHENKEL. F. S.; URBINATI, I.; CARVALHEIRO, R.; REGITANO, L. C. de A.; MARCONDES, C. R.; MINARI, D. P. Accuracy of genotype imputation in Canchim cattle using FImpute and Beagle software., In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Abstract... Guarujá:[ s.n.], 2013. AB.20.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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3. | | GARCIA, J. F.; CARMO, A. S. DO; UTSUNOMIYA, Y. T.; NEVES, H. H. DE R.; CARVALHEIRO, R.; TASSELL, C. V.; SONSTEGARD, T. S.; SILVA, M. V. G. B. How bioinformatics enables livestock applied sciences in the genomic era. In: BRAZILIAN SYMPOSIUM ON BIOINFORMATICS, 2012, Heidelberg. Proceedings... Porto Alegre: Sociedade Brasileira e Computação, 2012.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
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4. | | BOISON, S. A.; NEVES, H. H. R.; O'BRIEN, A. M. P.; UTSUNOMIYA, Y. T.; CARVALHEIRO, R.; SILVA, M. V. G. B.; SÖLKNER, J.; GARCIA, J. F. Imputation of non-genotyped individuals using genotyped progeny in Nellore, a Bos indicus cattle breed. Livestock Science, v. 166, p. 176-189, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite. |
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5. | | O'BRIEN, A. M. P.; MÉSZÁROS, G.; UTSUNOMIYA, Y. T.; SONSTEGARD, T. S.; GARCIA, J. F.; TASSEL, C. P. V.; CARVALHEIRO, R.; SILVA, M. V. G. B.; SÖLKNER, J. Linkage disequilibrium levels in Bos indicus and Bos taurus cattle using medium and high density SNP chip data and different minor allele frequency distributions. Livestock Science, v. 166, p. 121-132, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite. |
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6. | | BOISON, S. A.; UTSUNOMIYA, A. T. H.; SANTOS, D. J. A.; NEVES, H. H. R.; MÉSZÁROS, G.; CARVALHEIRO, R.; GARCIA, J. F.; SILVA, M. V. G. B.; SÖLKNER, J. Accuracy of genomic predictions for dairy traits in Gyr cattle (Bos indicus) Warsaw: EAAP, 2015.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
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7. | | SANTOS, N. P. da S.; SARMENTO, J. L. R.; CARVALHEIRO, R.; CAMPELO, J. E. G.; SOUSA, W. H. de; FIGUEIREDO FILHO, L. A. S.; REGO NETO, A. de A.; BIAGIOTTI, D. Contribuição genética ótima aplicada à seleção de ovinos Santa Inês. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 51, n. 6, p. 745-750, jun. 2016. Título em inglês: Optimum genetic contribution applied to the selection of Santa Ines sheep.Biblioteca(s): Embrapa Unidades Centrais. |
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8. | | MORALES, D. DA S.; SILVA, D. O.; AYRES, D. R.; SANTANA JÚNIOR, M. L.; BIGNARDI, A. B.; VENTURA, R. V.; MENEZES, G. R. de O.; CARVALHEIRO, R.; PICCOLI, M. L.; ROSO, V. M.; PEREIRA, R. J. Genetic associations between stayability to consecutive calvings and traits of economic interest in taurine and zebu breeds. Journal of Animal Breeding and Genetics, v. 140, 2023. 13 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Corte. |
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9. | | CAMPOS, G. S.; CARDOSO, F. F.; GULIAS GOMES, C. C.; DOMINGUES, R.; REGITANO, L. C. de A.; OLIVEIRA, M. C. de S.; OLIVEIRA, H. N. DE; CARVALHEIRO, R.; ALBUQUERQUE, L. G.; MILLER, S.; MISTZAL, I.; LOURENCO, D. Development of genomic predictions for Angus cattle in Brazil incorporating genotypes from related american sires. Journal of Animal Science, v. 100, n. 2, p. 1-13, Feb. 2022. skac009.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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10. | | CHUD, T. C. S.; VENTURA, R. V.; SCHENKEL, F. S.; CARVALHEIRO, R.; BUZANSKAS, M. E.; ROSA, J. O.; MUDADU, M. de A.; SILVA, M. V. G. B.; MARCONDES, C. R.; REGITANO, L. C. de A.; MUNARI, D. P. Strategies for genotype imputation in composite beef cattle BMC Genetics, v. 16, p. 99, 2015. 10 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite. |
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11. | | BOISON, S. A.; SANTOS, D. J. A.; UTSONOMIYA, A. H. T.; CARVALHEIRO, R.; NEVES, H. H. R.; O'BRIEN, A. M. P.; GARCIA, J. F.; SÖLKNER, J.; SILVA, M. V. G. B. Strategies for single nucleotide polymorphism (SNP) genotyping to enhance genotype imputation in Gyr (Bos indicus) dairy cattle: Comparison of commercially available SNP chips. Journal of Dairy Science, v. 98, n. 7, p. 4969-4989, 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Leite. |
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12. | | NEVES, H. H.; CARVALHEIRO, R.; O'BRIEN, A. M.; UTSUNOMIYA, Y. T.; CARMO, A. S. do; SCHENKEL, F. S.; SÖLKNER, J.; MCEWAN, J. C.; VAN TASSELL, C. P.; COLE, J. B.; SILVA, M. V. G. B.; QUEIROZ, S. A.; SONSTEGARD, T. S.; GARCIA, J. F. Accuracy of genomic predictions in Bos indicus (Nellore) cattle. Genetics Selection Evolution, v. 46, article 17, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 4 |
Biblioteca(s): Embrapa Gado de Leite. |
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13. | | BOISON, S. A.; UTSUNOMIYA, A. T. H.; SANTOS, D. J. A.; NEVES, H. H. R.; CARVALHEIRO, R.; MÉSZÁROS, G.; UTSUNOMIYA, Y. T.; CARMO, A. S. do; VERNEQUE, R. da S.; MACHADO, M. A.; PANETTO, J. C. do C.; GARCIA, J. F.; SÖLKNER, J.; SILVA, M. V. G. B. Accuracy of genomic predictions in Gyr (Bos indicus) dairy cattle. Journal of Dairy Science, v. 100, n. 7, p. 5479-5490, 2017.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Leite. |
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14. | | ZAVAREZ, L. B.; UTSUNOMIYA, Y. T.; CARMO, A. S.; NEVES, H. H.; CARVALHEIRO, R.; FERENCAKOVIC, M.; O'BRIEN, A. M. P.; CURIK, I.; COLE, J. B.; TASSELL, C. P. V.; SILVA, M. V. G. B.; SONSTEGARD, T. S.; SÖLKNER, J.; GARCIA, J. F. Assessment of autozygosity in Nellore cows (Bos indicus) through high-density SNP genotypes. Frontiers in Genetics, v. 6, n. 5, p. 286-293, 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite. |
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15. | | O'BRIEN, A. M. P.; HÖLLER, D.; BOISON, S. A.; MILANESI, M.; BOMBA, L.; UTSUNOMIYA, Y. T.; CARVALHEIRO, R.; NEVES, H. H. R.; SILVA, M. V. G. B.; VAN TASSEL, C. P.; SOSTENGARD, T. S.; MÉSZÁROS, G.; AJMONE-MARSAN, P.; GARCIA, J. F.; SÖLKNER, J. Low levels of taurine introgression in the current Brazilian Nelore and Gir indicine cattle populations. Genetics Selection Evolution, v. 47, article 31, 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Leite. |
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16. | | UTSUNOMIYA, Y. T.; CARMO, A. S. do; CARVALHEIRO, R.; NEVES, H. H. R.; MATOS, M. C.; ZAVAREZ, L. B.; O'BRIEN, A. M. P.; SÖLKNER, J.; McEWAN, J. C.; COLE, J. B.; TASSEL, C. P. V.; SCHENKEL, F. S.; SILVA, M. V. G. B.; PORTO NETO, L. R.; SONSTEGARD, T. S.; GARCIA, J. F. Genome-wide association study for birth weight in Nellore cattle points to previously described orthologous genes affecting human and bovine height. BMC Genetics, London, v. 14, article 52, 2013.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Leite. |
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17. | | UTSUNOMIYA, Y. T.; CARMO, A. S.; NEVES, H. H. R.; CARVALHEIRO, R.; MATOS, M. C.; ZAVAREZ, L. B.; ITO, P. K. R. K.; O'BRIEN, A. M. P.; SOLKNER, J.; PORTO-NETO, L. R.; SCHENKEL, F. S.; McEWAN, J.; COLE, J. B.; SILVA, M. V. G. B.; VAN TASSELL, C. P.; SONSTEGARD, T. S.; GARCIA, J. F. Genome-wide mapping of loci explaining variance in scrotal circumference in Nellore Cattle. Plos One v. 9, n. 2, p. 1-9, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Leite. |
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18. | | CARDOSO, D. F.; FERNANDES JÚNIOR, G. A.; SCALEZ, D. C. B.; ALVEZ, A. A. C.; MAGALHÃES, A. F. B.; BRESOLIN, T.; VENTURA, R. V.; LI, C.; OLIVEIRA, M. C. de S.; PORTO NETO, L. R.; CARVALHEIRO, R.; OLIVEIRA, H. N. de; TONHATI, H.; ALBUQUERQUE, L. G. Uncovering sub-structure and genomic profiles in across-countries subpopulations of Angus Cattle. Scientific Reports, v. 10, article 8770, 2020. 11 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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19. | | CHUD, T. C. S.; VENTURA, R. V.; SCHENKEL, F. S.; CARVALHEIRO, R.; BUZANSKAS, M. E.; ROSA, J. O.; MUDADU, M. de A.; SILVA, M. V. G. B.; MOKRY, F. B.; MARCONDES, C. R.; REGITANO, L. C. de A.; MUNARI, D. P. Strategies for genotype imputation in composite beef cattle. BMC Genomics, v. 16, n. 99, 2015. 10 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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20. | | SÖLKNER, J.; PEREZ O'BRIEN, A. M.; HÖLLER, D.; BOISON, S. A.; MILANESI, M.; BOMBA, L.; UTSUNOMIYA, Y. T.; CARVALHEIRO, R.; NEVES, H. H. R.; SILVA, M. V. G. B.; VAN TASSEL, C. P.; SOSTENGARD, T. S.; MÉSZÁROS, G.; AJMONE-MARSAN, P.; GARCIA, J. F. Zebuines kerngenom und taurine Mitochondrien: admixtur von Nelore, der größten brasilianischen rinderrasse. Nova Acta Leopoldina, NF 119, n. 404, p. 69-75, 2016.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
Biblioteca(s): Embrapa Gado de Leite. |
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Registros recuperados : 20 | |
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Nenhum registro encontrado para a expressão de busca informada. |
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